Transports of delight

نویسندگان

  • Lelio Orci
  • C Barlowe
  • L Orci
  • T Yeung
  • M Hosobuchi
  • S Hamamoto
  • N Salama
  • M Rexach
  • M Ravazzola
  • M Amherdt
  • S Y Bednarek
  • A Perrelet
  • R Schekman
چکیده

pictures above are of purified intracellular transport vesicles. Each has a 'COP II' membrane coat made up of Sec proteins (first identified for their function in secretion from yeast cells). The vesicles transport secretory and membrane proteins from the endoplasmic reticulum to the Golgi complex in yeast, and homologous COP II components have been identified in plants and in mammalian cells. The vesicles shown here were isolated from yeast endoplasmic reticulum membranes to which purified COP II components were added, to promote budding. Identical vesicles can be budded from the yeast nuclear envelope, a source of 'pure' endoplasmic reticulum. Two of the views (left and right) are conventional thin sections, with the low-power shot revealing the purity of the preparations. The other two (top and bottom) are quick-frozen deep-etch replicas, revealing the surface structure of the COP II coat. In the bottom image, one coat component has been immunolabelled with gold particles, which appear as white dots.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Transports of Delight

Intrinsic optical signals, evoked by neural activity, provide an essentially noninvasive means of monitoring the organization of brain circuitry. A new study by Gurden et al. in this issue of Neuron reveals a surprising role of astrocyte glutamate transporters in generating these signals.

متن کامل

A Study on the Effect of Life Satisfaction on the Social Delight

This research tries to study the role and the effect of life satisfaction on the social delight among the students. This descriptive research studies 350 students at I.A.U of Tehran Eastren branch. Through a survey study, the data coefficient. The result show that move than 75% of students  were moderately pleased from their life, thus there is a positive and significant relationship between li...

متن کامل

A Trivalent Approach to the Quality of the “Khoshk” River Landscape in Shiraz

By considering certain factors like those mentioned by Ian Thompson (2005) in his definition of landscape, i.e. ecology, community and delight, in designing landscapes, one can find the vocation more applicable and useful. City rivers can play a very important role with regard to such values. In fact, the presence of nature and wildlife could not only be the lifeline of a city, but also a facto...

متن کامل

The Teacher's Perspective on How to Delight Schools Considering the Physical Standards

Joy and happiness has always been as one of the most important needs of students and teachers at schools. Studies have shown that physical factors, management, and relationships at school are involved in creating happiness in teachers and students. In the present study, our main focus is on the physical aspect of schools, which should be in accordance with the standards of education, according...

متن کامل

A Random Walk with Exponential Travel Times

Consider the random walk among N places with N(N - 1)/2 transports. We attach an exponential random variable Xij to each transport between places Pi and Pj and take these random variables mutually independent. If transports are possible or impossible independently with probability p and 1-p, respectively, then we give a lower bound for the distribution function of the smallest path at point log...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Current Biology

دوره 6  شماره 

صفحات  -

تاریخ انتشار 1996